Markus W Büchler Selected Research

Phosphotransferases (Kinase)

11/2011	Correlation of gene expression of ATP-binding cassette protein and tyrosine kinase signaling pathway in patients with hepatocellular carcinoma.
11/2010	Sorafenib modulates the gene expression of multi-drug resistance mediating ATP-binding cassette proteins in experimental hepatocellular carcinoma.
10/2007	PKC 412 small-molecule tyrosine kinase inhibitor: single-compound therapy for pancreatic cancer.
7/2004	Gefitinib ('Iressa', ZD1839), a selective epidermal growth factor receptor tyrosine kinase inhibitor, inhibits pancreatic cancer cell growth, invasion, and colony formation.
1/2004	Antiangiogenic activity of genistein in pancreatic carcinoma cells is mediated by the inhibition of hypoxia-inducible factor-1 and the down-regulation of VEGF gene expression.
11/2003	Reverse transcription-PCR analysis of laser-captured cells points to potential paracrine and autocrine actions of neurotrophins in pancreatic cancer.

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Markus W Büchler Research Topics

Disease

196	Neoplasms (Cancer) 02/2024 - 01/2002
186	Pancreatic Neoplasms (Pancreatic Cancer) 12/2023 - 01/2002
66	Adenocarcinoma 10/2023 - 04/2002
44	Chronic Pancreatitis 09/2017 - 04/2001
40	Neoplasm Metastasis (Metastasis) 02/2024 - 01/2002
39	Pancreatitis 04/2022 - 01/2002
30	Pancreatic Fistula (Pancreatic Fistulas) 01/2024 - 01/2002
21	Rectal Neoplasms (Rectal Cancer) 01/2021 - 01/2005
20	Pain (Aches) 01/2020 - 04/2001
17	Hemorrhage 01/2024 - 06/2002
14	Infections 01/2023 - 01/2002
14	Inflammation (Inflammations) 01/2020 - 04/2001
14	Reperfusion Injury 01/2018 - 07/2004
13	Colorectal Neoplasms (Colorectal Cancer) 05/2024 - 09/2002
13	Hepatocellular Carcinoma (Hepatoma) 10/2023 - 03/2004
13	Margins of Excision 01/2021 - 01/2008
12	Wounds and Injuries (Trauma) 01/2020 - 04/2002
12	Necrosis 01/2018 - 01/2002
10	Ischemia 01/2023 - 04/2005
10	Carcinoma (Carcinomatosis) 01/2022 - 04/2002
10	Anastomotic Leak 11/2021 - 05/2002
9	Sepsis (Septicemia) 05/2024 - 06/2002
9	Acute Cholecystitis 08/2015 - 01/2007
8	Postoperative Pain 01/2021 - 11/2006
8	Cholangitis 04/2020 - 01/2007
8	Fibrosis (Cirrhosis) 11/2013 - 04/2002
7	Fistula 07/2023 - 08/2006
7	Hypoxia (Hypoxemia) 02/2012 - 01/2003
6	Colonic Neoplasms (Colon Cancer) 05/2024 - 08/2007
6	Surgical Wound Infection 05/2024 - 11/2011
6	Obesity 11/2023 - 10/2006
6	Acute Necrotizing Pancreatitis 07/2023 - 01/2002
6	Thrombosis (Thrombus) 01/2022 - 01/2005
6	Incisional Hernia 10/2021 - 03/2005
6	Esophageal Neoplasms (Esophageal Cancer) 01/2021 - 04/2002
6	Diabetes Mellitus 01/2020 - 10/2006
6	Wound Infection (Wound Infections) 12/2018 - 07/2004
6	End Stage Liver Disease 01/2014 - 09/2005
5	Liver Failure 01/2022 - 09/2002
5	Cysts 01/2019 - 01/2004
5	Type 2 Diabetes Mellitus (MODY) 09/2017 - 06/2013
5	Disease Progression 01/2016 - 08/2005

Drug/Important Bio-Agent (IBA)

60	Messenger RNA (mRNA)IBA 11/2021 - 04/2001
42	Proteins (Proteins, Gene)FDA Link 11/2020 - 08/2002
18	Gemcitabine FDA Link 01/2023 - 01/2002
14	EnzymesIBA 01/2022 - 01/2002
14	Anti-Bacterial Agents (Antibiotics)IBA 12/2018 - 01/2002
13	AntigensIBA 12/2022 - 04/2005
13	Biomarkers (Surrogate Marker)IBA 01/2022 - 08/2009
12	Fluorouracil (Carac)FDA LinkGeneric 02/2023 - 01/2002
12	LigandsIBA 02/2020 - 01/2002
9	Insulin (Novolin)FDA Link 09/2017 - 03/2003
9	CytokinesIBA 09/2017 - 01/2003
9	Transforming Growth Factor beta (TGF-beta)IBA 05/2007 - 01/2002
8	RNA (Ribonucleic Acid)IBA 10/2023 - 04/2002
8	CeruletideIBA 03/2012 - 03/2004
8	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2011 - 12/2002
8	AntibodiesIBA 04/2010 - 10/2002
8	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2006 - 09/2002
7	folfirinoxIBA 04/2023 - 01/2016
6	Leucovorin (Folinic Acid)FDA Link 02/2023 - 09/2010
6	C-Reactive ProteinIBA 12/2022 - 01/2007
6	Oxygen (Dioxygen)IBA 01/2021 - 01/2003
6	Phosphotransferases (Kinase)IBA 11/2011 - 11/2003
6	GlucocorticoidsIBA 01/2009 - 03/2006
5	AlbuminsIBA 12/2022 - 03/2004
5	Amylases FDA Link 01/2021 - 09/2007
5	Tyrosine Kinase InhibitorsIBA 03/2016 - 11/2002
5	Epithelial Cell Adhesion MoleculeIBA 06/2015 - 09/2009
5	DNA (Deoxyribonucleic Acid)IBA 02/2015 - 01/2003
5	Neoplasm Antigens (Tumor Antigens)IBA 02/2015 - 11/2005

Therapy/Procedure

90	Therapeutics 02/2024 - 06/2002
50	Drug Therapy (Chemotherapy) 02/2024 - 01/2002
44	Pancreatectomy 01/2024 - 12/2003
40	Pancreaticoduodenectomy 01/2024 - 04/2002
37	Neoadjuvant Therapy 01/2023 - 08/2008
26	Length of Stay 05/2024 - 11/2005
21	Liver Transplantation 10/2019 - 07/2004
18	Adjuvant Chemotherapy 01/2023 - 03/2004
16	Radiotherapy 02/2020 - 05/2002
15	Chemoradiotherapy 01/2023 - 03/2004
14	Transplantation 01/2022 - 07/2004
13	Operative Surgical Procedures 12/2020 - 06/2002
12	Laparotomy 10/2021 - 01/2004
11	Lymph Node Excision (Lymph Node Dissection) 05/2023 - 01/2004
11	Cholecystectomy 08/2015 - 01/2002
9	Hepatectomy 11/2023 - 03/2009
9	Lasers (Laser) 01/2021 - 06/2002
9	Sutures (Suture) 10/2014 - 01/2002
7	Immunotherapy 10/2023 - 08/2005
6	Ligation 11/2023 - 09/2007
6	Operative Time 07/2023 - 03/2006
6	Esophagectomy 01/2021 - 08/2006
6	Gastric Bypass (Roux-en-Y Gastric Bypass) 09/2017 - 01/2012
6	Proctectomy 01/2017 - 03/2007
6	Critical Care (Surgical Intensive Care) 08/2011 - 01/2002
5	Stents 11/2021 - 03/2005
5	Gastrectomy 10/2021 - 12/2004
5	Ileostomy 10/2020 - 02/2011
5	Kidney Transplantation 01/2020 - 07/2004